Dr. Mindrum’s Corner

A space for exploration.

Thoughts on obesity, medicine, research, clinical insights, health, wellness, perspective, and anything else that sparks curiosity.

April 5, 2026 · MASLD · Glucagon · Type 2 Diabetes

MASLD & Glucagon: The Liver That Stops Listening

Glucagon is supposed to tell the liver to burn fat, so why do newly diagnosed type 2 diabetes and fatty liver so often arrive together? A 2026 Diabetes Care study by Huttasch and colleagues points to a liver that has stopped listening.

Read the post ›
April 7, 2026 · Reflection · Running · Recovery

On Windmills and Giants

Twenty years of running injuries, a broken neck in Costa Rica, and a coach on a treadmill screen who taught me to rebuild slowly, layer by layer. A reflection on patience, foundation, and the giants we run with.

Read the post ›
June 3, 2025 · Genetics · Obesogenic Environment · Bias and Stigma

Obesity and Genetics: How Heritability and Environment Interact

How can genes explain an obesity epidemic that has escalated over the past 50 years when our genes haven’t changed? A story about how genes and environment shape obesity — and what it means for a kinder, healthier world.

Read the post ›
May 31, 2025 · Cholesterol · Low Carb Diet · Nutrition

The Perils of Causal Claims in the KETO-CTA Observational Study

Why omitting a pre-registered primary endpoint and using causal language for exploratory findings is a concerning lapse in scientific standards — and how it could lead clinicians to withhold proven lipid-lowering therapy.

Read the post ›